Improving disease resistance of zebrafish and trout fed prebiotics and probiotics

David Huyben, Junyu Zhang, Nancy Gao, Mary Wang, Nicole Moran, Umesh Shandilya, Niel Karrow

Prebiotic fibre and probiotic bacteria and yeast have been toted as health promotants in humans, pets and now for farmed animals. However, their impact on improving disease resistance is not well known in fish. Zebrafish (Danio rerio) are a great model species since they are easy to handle, breed and their genome has been intensely studied. We aim to link effects of pre/probiotics with the immune and microbiome responses of zebrafish and validate this with rainbow trout.